A progressive genetic muscle wasting disease

Facts & Figures

Duchenne muscular dystrophy is a rare, genetic disease.

Duchenne muscular dystrophy is the most common fatal genetic disorder diagnosed in childhood. It is an X-linked disease that is caused by mutations in the dystrophin gene, which leads to the absence of the dystrophin protein. The disease occurs in approximately one in every 3,500-5,000 boys born and has no ethnic, geographic, racial or religious boundaries.

Diagnosis usually comes between the ages of three and five due to pronounced muscle weakness. Unable to live normal lives because of progressive and irreversible muscle loss, patients typically lose the ability to walk by their early teens and succumb to respiratory or heart failure in their 30s. DMD is 100% fatal.

No Cure

There is no cure for Duchenne muscular dystrophy, and there is only one treatment on the market that is approved for a small subset of patients. Solid is purpose-built to identify and develop the most promising approaches to address the disease at all stages.

Stages of Duchenne Age Physical Manifestation
Early Phase Ages of 2 to 7 Delays in early developmental milestones
Transitional Phase Ages of 6 to 9 Difficulty walking due to muscle weakness
Loss of Ambulation Ages of 10 to 14

Use of power wheelchair on a regular basis. Activities involving the arms, legs or trunk will require assistance

Adult Stage Ages 15+ Life-threatening heart and respiratory conditions become more prevalent

 

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